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Quality of Life in Epilepsy Inventory (QOLIE-31)

A 31-item self-reported quality-of-life scale for people with epilepsy.

By Claire White

What it measures

The QOLIE-31 covers seven health-related quality-of-life domains that matter to people with epilepsy. Seizure worry (5 items) captures fear of seizures. Overall quality of life (2 items) is a global rating. Emotional well-being (5 items) covers mood and distress. Energy/fatigue (4 items), cognitive functioning (6 items), medication effects (3 items), and social functioning (5 items) complete the scale. One additional item (driving limitations) is not scored.

What the result tells you

Subscale and overall scores (0 to 100, higher means better quality of life) reflect how epilepsy affects daily life. The scale is sensitive to change with treatment and is used in trials of anti-seizure medications and surgical interventions. It captures burden beyond seizure frequency, including side effects and psychosocial impact.

Used for

Evidence, psychometrics and provenance

Psychometrics

Internal consistencyCronbach α 0.72–0.87
Test-retest reliabilityr 0.75–0.84

Reliability on a 0 to 1 scale. Higher is better.

References

  1. 1.Devinsky O, Vickrey BG, Cramer J, et al. Development of the quality of life in epilepsy inventory. Epilepsia. 1995;36(11):1089-1104.

This assessment uses a validated instrument and is reference information, not a diagnosis.