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MDS-Unified Parkinson’s Disease Rating Scale (MDS-UPDRS)

The standard rating scale for Parkinson’s disease, covering motor and non-motor domains across four parts.

By Claire White

The four parts

What it measures

The MDS-UPDRS has four parts. Part I (non-motor experiences of daily living, 0 to 52) and Part II (motor experiences of daily living, 0 to 52) are completed by the patient. Part III (motor examination, 0 to 132) is administered by a clinician and covers tremor, rigidity, bradykinesia, gait, and postural instability. Part IV (motor complications, 0 to 24) rates dyskinesias and fluctuations.

What the result tells you

Lower total scores indicate less impairment. The scale tracks disease progression and treatment response in clinical practice and trials. MDS-UPDRS Part III is the most frequently used standalone measure in motor outcome studies. Each part can also be used independently.

Used for

Evidence, psychometrics and provenance

Psychometrics

Internal consistency (Part III)Cronbach α = 0.93
Inter-rater reliability (Part III)ICC 0.90–0.99

Part III reliability on a 0 to 1 scale. Higher is better.

References

  1. 1.Goetz CG, et al. Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results. Mov Disord. 2008;23(15):2129-2170.

This assessment uses a validated instrument and is reference information, not a diagnosis. The MDS-UPDRS is © 2008 the Movement Disorder Society and is used under licence.