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MDS-UPDRS Part I – Non-Motor Experiences of Daily Living

Non-motor experiences of daily living in Parkinson’s disease. 13 items, total 0 to 52.

By Claire White

What it measures

Part I covers 13 non-motor symptoms experienced in daily life. Items 1.1 to 1.6 (cognitive impairment, hallucinations, delusions, depressed mood, anxious mood, apathy, dopamine dysregulation syndrome) are completed with clinician input. Items 1.7 to 1.13 (sleep problems, daytime sleepiness, pain, urinary problems, constipation, light-headedness, fatigue) are completed by the patient independently.

What the result tells you

Higher Part I scores indicate greater non-motor burden. Non-motor symptoms are often undertreated in Parkinson’s disease, and Part I quantifies them systematically. It is used in trials of symptomatic therapies and in longitudinal registry studies tracking disease progression.

Used for

Evidence, psychometrics and provenance

This assessment uses a validated instrument and is reference information, not a diagnosis. The MDS-UPDRS is © 2008 the Movement Disorder Society and is used under licence.